October 16, 2024
Acid-Base Disorders in CDI: Lactic Acidosis Query and ICD-10-CM Coding Guidance
Clinical Scenario: Acid-Base Imbalance in Crohn’s Disease
H&P: 51-year-old female with Crohn’s disease, morbid obesity, and a BMI of 42 presents from home in a private vehicle with 4 days of fever, severe abdominal pain, diarrhea, and nausea and vomiting.
Patient History, Vitals, and Clinical Findings
PMH: Hypertension, Crohn’s disease, and CKD Stage 3a with a baseline creatinine of 1.2
Home Medications: Stelera 90 mg SQ every 8 weeks (last dose 6 weeks ago), Prednisone 20 mg PO daily, Metoprolol 50 mg PO BID, and Lisinopril 20 mg PO daily
Vitals: B/P 99/56, HR 89, Temp 100.8, RR 18, Pulse ox 96% on room air
PE: Abdomen TTP, scant dark urine
Labs: Lactic Acid 4.2, WBC 18.5, Creatinine 1.5, CRP 105. Repeat lactic acid after fluid bolus 3.0 and 1.5.
CT: Abdomen revealing small-bowel wall thickening, mesenteric inflammatory stranding, and mesenteric adenopathy, partial small bowel obstruction. Impression: Crohn’s disease with partial obstruction
Treatment Course and Discharge Summary
Consult: GI consulted, NGT placed, started IV prednisone to be tapered to PO once pain subsides and having bowel movements again.
Discharge Summary: Crohn’s flare with partial small bowel obstruction. Treated with NGT tube, IV prednisone, pain medication, 2 L normal saline bolus & normal saline continuous IV @ 75 ml/hr. Patient is tolerating PO intake and having normal bowel movements. Outpatient GI follow-up in 1 week.
Discharge Medication: Prednisone increased to 40 mg PO daily, resume home medications of Metoprolol 50 mg PO BID, and Lisinopril 20 mg PO daily, and normal Stelera injection in 10 days.
CDI Query Opportunity: Lactic Acidosis
Question: Are there query opportunities based on the scenario stated above?
Discussion: The patient has exhibited the following risk factors and clinical indicators: 4 days of abdominal pain, diarrhea, and nausea & vomiting. Lactic Acid 4.2 with repeat lactic acid after fluid bolus 3.0 and 1.5. Crohn’s disease with partial small bowel obstruction and CKD stage 3a.
Diagnostic Criteria for Lactic Acidosis
Lactic acid > 4
Lactic Acid > 2 plus pH < 7.35
Lactic Acid > 2 plus Anion gap > 12
Treatment Indicators Supporting Lactic Acidosis
Normal saline IV fluid bolus 2,000 ml
Normal saline IV continuous rate 75 ml/hr
UASI Recommends: Query for Lactic Acidosis
Impact of Documentation on Coding and DRG
Documentation without clarification:
Principal Diagnosis: K50.012 Crohn’s disease of small intestine with intestinal obstruction
Secondary Diagnosis: E66.01 Morbid obesity, Z68.41 BMI 40.0-44.9 adult
Working DRG: 386 Inflammatory bowel disease with CC
RW: 0.9898
GLMOS: 3.4
SOI/ROM: 1/1
Documentation with clarification:
Principal Diagnosis: K50.012 Crohn’s disease of small intestine with intestinal obstruction
Secondary Diagnosis: E66.01 Morbid obesity, Z68.41 BMI 40.0-44.9 adult, E87.20 Acidosis, unspecified
Working DRG: 386 Inflammatory bowel disease with CC
RW: 0.9898
GLMOS: 3.4
SOI/ROM: 2/2
CDI Educational Tips for Acid-Base Disorders
Acidosis is classified to code E87.20. Inclusion terms are lactic acidosis and metabolic acidosis.
E87.20 provides a CC as a secondary diagnosis.
The treatment of metabolic acidosis and alkalosis depends entirely on its cause. The underlying cause should also be treated.
Conditions often associated with acid/base imbalance include diarrhea, poisoning (metabolic acidosis), vomiting, dehydration (metabolic alkalosis), sepsis (elevated lactate), and COPD (respiratory acidosis).
Interpreting Lactate Levels and Clinical Significance
An elevated lactate/lactic acid does not necessarily indicate lactic acidosis which requires elevated lactate in addition to acidosis (pH<7.35). Lactate levels < 2.0 are normal, and transient slight elevations are often not clinically significant. For example, a slightly elevated lactate of 2.2 on admission for which the lactate level is simply repeated.
Laboratory Indicators of Acidosis or Alkalosis
| Test | Value | Indicates | ICD-10 Code |
|---|---|---|---|
| CO2 (bicarbonate) | > 28 or < 22 | Metabolic alkalosis / Metabolic acidosis | E87.3, E87.20 - E87.22 |
| Chloride | > 106 | Metabolic acidosis, NAGMA / Renal tubular acidosis | E87.20 - E87.22, N25.89 |
| Lactate / Lactic Acid | > 4, > 2 + pH < 7.35, > 2 + AGAP > 12 | Lactic Acidosis | E87.20 - E87.22 |
| Anion gap (AGAP) | > 12 | Anion Gap Metabolic Acidosis | E87.29 |
| ABG / VBG | Value | Indicates | ICD-10 Code |
| HCO3 (bicarbonate) | > 28 or < 22 | Metabolic alkalosis / Metabolic acidosis | E87.3, E87.20 - E87.22 |
| pH | < 7.35 / > 7.45 / > 7.45 + pCO2 < 35 | Acidosis / Alkalosis / Respiratory Alkalosis | E87.20, E87.3, E87.3 |
| pCO2 | > 45 / > 50 (> 55 VBG) + pH < 7.35 / > 50 (> 55 VBG) + pH normal / < 35 + pH > 7.45 | Respiratory Acidosis / Acute Respiratory Acidosis / Chronic Respiratory Acidosis / Respiratory Alkalosis | E87.29, J96.02, J96.12, E87.3 |
Important Disclaimer
This is a short synopsis of a possible patient record and is not intended to be all-inclusive. This is for educational purposes only and not intended to replace your institutional guidelines.
Works Cited
Association of Clinical Documentation Integrity Specialists (ACDIS). (2023). Acid-base disorders. Available at: https://pro.acdis.org/inpatient/conditions/acid-base-disorders
Pinson, R., & Tang, C. (2023). CDI Pocket Guide. Available at: https://cdiplus.com













