Presymptomatic Type 1 Diabetes Staging: ICD-10-CM Updates Effective FY 2025

Overview of ICD-10-CM Updates for Presymptomatic Diabetes

ICD-10 is expanding subcategory E10 to identify stages of Presymptomatic Diabetes Mellitus 

Come October 1, we will now be able to identify diabetes at earlier presymptomatic stages. ICD -10 is expanding subcategory E10 to identify stage1 and 2 presymptomatic diabetes. 

Understanding the Three Stages of Type 1 Diabetes

Type 1 diabetes can now be most accurately understood as a disease that progresses in three distinct stages.

STAGE 1 is the start of type 1 diabetes. Individuals test positive for two or more diabetes-related autoantibodies. The immune system has already begun attacking the insulin-producing beta cells, although there are no symptoms and blood sugar remains normal.

STAGE 2, like stage 1, includes individuals who have two or more diabetes-related autoantibodies, but now, blood sugar levels have become abnormal due to increasing loss of beta cells. There are still no symptoms.

STAGE 3 is when clinical diagnosis typically takes place. By this time, there is significant beta cell loss and individuals generally show common symptoms of type 1 diabetes, which include frequent urination, excessive thirst, weight loss, and fatigue.

Works Cited

Type 1 Diabetes TrialNet. (n.d.). Type 1 diabetes staging classification opens door for intervention. Available at: https://www.trialnet.org/events-news/blog/type-1-diabetes-staging-classification-opens-door-intervention